Archive for the 'Bioinformatics' Category



Virtual Reality Used to Cure Phantom Limb Pain

Today, slashdot.org had a post concerning the use of Virtual Reality (VR) technology to cure phantom limb pain (PLP). PLP is the sensation one may feel after the loss of a limb via amputation. For example lets say a person’s left leg is amputated due to diabetes but they still feel pain in their left foot even though they no longer have that limb; this is PLP. The Virtual Reality comes into play by tricking the amputee’s brain into believing they still have the limb and therefore reduces pain felt in PLP.

Some may differ in this opinion but I consider this to be bioinformatics related since its the use of computer science techniques to address a biological or clinical problem. What does everyone else think?

Artificial Intelligence and Cancer Research

I attended a talk today, concerning the use of artificial intelligence (AI) in cancer research.  Dr. Paul Brooks discussed his research using AI to study a particular treatment of sarcoma, a cancer in the supportive tissues of the body (i.e. blood vessels, bones, muscles, etc).

He described the need to use computer algorithms to improve brachytherapy, a method that can be applied post removal of a tumor.  What brachytherapy does is insert sealed sources of radiotherapy around the the area from where the tumor was removed to treat the leftover diseased tissue.  In the abstract of his publiction Dr. Brooks describes the current practice of determining the area for brachytherapy treatment to be a “tedious manual process”. 

What his research entailed was using AI to automatically classify the contours of how the radiotherapy sources were to be placed.  The AI would be able to distinguish between various structures of sarcoma tumour beds and suggest the best placement for the radiotherapy treatment.

I’m not sure about any other bioinformaticians out there but its pretty exciting to see computer science and biology merged together for actual clinical application.

Dr. Brooks’s abstract can be found here via PubMed.

Hooray for Bioinformatics!

The BBC news had a report last week on a UK Scientist winning a large international prize with his work in E. Coli. What was supposed special about his work is that he used computers to model a part of the biological system of E. Coli. Its nice to see Bioinformatics (or Computational Biology) recognized internationally. If you want to know more you can read the article here.